Next generation maternal health: external shocks and health-system innovations

Maternal nutrition: effects on health in the next generation.

Nearly 20 years ago, it was discovered that low birthweight was associated with an increased risk of adult diabetes and cardiovascular disease (CVD). This led to the hypothesis that exposure to undernutrition in early life increases an individual's vulnerability to these disorders, by 'programming' permanent metabolic changes. Implicit in the programming hypothesis is that improving the nutriti...

Nurturing Societal Values in and Through Health Innovations; Comment on “What Health System Challenges Should Responsible Innovation in Health Address?”

Aligning innovation processes in healthcare with health system demands is a societal objective, not always achieved. In line with earlier contributions, Lehoux et al outline priorities for research, public communication, and policy action to achieve this objective. We endorse setting these priorities, while also highlighting a ‘commitment gap’ in collectively addressing system-level challenges....

Improving Birth Rate in Iran with Minimizing Cesarean Deliveries: Less Maternal Mortality and Better Health and Education for the Next Generation

Health system innovations: adapting to rapid change

This paper introduces the Thematic Issue on Innovation in Health Systems in Low- and Middle-Income Countries.

Next-generation phenotyping of electronic health records

The national adoption of electronic health records (EHR) promises to make an unprecedented amount of data available for clinical research, but the data are complex, inaccurate, and frequently missing, and the record reflects complex processes aside from the patient's physiological state. We believe that the path forward requires studying the EHR as an object of interest in itself, and that new ...